PR10333_启动子库_赢润生物
您好,欢迎光临赢润生物技术商城
请登录    |     免费注册     帮助中心

客服热线:18507311342

QQ咨询:7128088

订货邮箱:service@yrgene.com

当前位置: 首页 > 启动子库

启动子产品信息

订购信息

货号 种属 载体 描述 价格 周期
PR10333 Human pGL3-basic 询价 3-4 周

产品参数

Gene Promoter: Human Epididymis Protein 4
Specificity: Tumor
Backbone: pDRIVE, pDRIVE5-SEAP, pGL3-basic, pUC57, pcDNA3.1-EGFP, ect.

产品说明书

pDRIVE-HE4(human) Map 产品说明书(点击下载)

产品说明

Description:
The human epididymis protein 4 (HE4), a member of the whey-acidic protein family, is frequently overexpressed in ovarian cancer cells. Upregulation of whey-acidic proteins in cancer appears to be due to a transcriptional event. A 652 bp fragment of the HE4 promoter, from -530 to +122 (relative to the ATG start site of HE4), is capable of restricting the expression of a transgene to ovarian tumor cells. The HE4-652 promoter contains a cAMP inducible element and seven Ap1 sites. Several hormonal responsive elements and inflammatory responsive elements are found within the promoter that may contribute to the high expression of HE4 in ovarian cancer.


1. Berry NB. et al., 2004. Transcriptional targeting in ovarian cancer cells using the human epididymis protein 4 promoter. Gynecol Oncol. 92(3):896-904.

立即购买 加入购物车

长沙赢润生物技术有限公司版权所有 湘ICP备15013987号-2