启动子产品信息
订购信息
货号 |
种属 |
载体 |
描述 |
价格 |
周期 |
PR10173 |
Human |
pcDNA3.1-EGFP |
|
询价
|
3-4 周 |
产品参数
Gene Promoter: Monocyte Receptor for Bacterial LPS
Specificity: Monocytic cells
Backbone: pDRIVE, pDRIVE5-SEAP, pGL3-basic, pUC57, pcDNA3.1-EGFP, ect.
产品说明书
pDRIVE-CD14(human) Map 产品说明书(点击下载)
pDRIVE5-SEAP-CD14(human) Map 产品说明书(点击下载)
pDRIVE5-SEAP-CD14(human) Sequence 产品说明书(点击下载)
产品说明
Description:
CD14 is a receptor for bacterial lipopolysaccharide expressed on the surface of myeloid-derived cells, and is strongly upregulated during monocytic cell differentiation. Monocyte-specific expression of CD14 is regulated at the transcriptional level. The CD14 promoter contains a C/EBP [1] and Sp1 [2] site that are critical for tissue-specific regulation of CD14 gene expression.
1. Pan Z. et al. 1999. CCAAT/enhancer-binding protein activates the CD14 promoter and mediates transforming growth factor beta signaling in monocyte development. J Biol Chem 274(33):23242-8.
2. Park S. et al. 2002. Synergistic interaction of MEF2D and Sp1 in activation of the CD14 promoter. Mol Immunol 39(1-2):25.
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