启动子产品信息
订购信息
货号 |
种属 |
载体 |
描述 |
价格 |
周期 |
PR10129 |
Human |
pDrive |
|
询价
|
3-4 周 |
产品参数
Gene Promoter: Beta-Kinesin
Specificity: Ubiquitous
Backbone: pDRIVE, pDRIVE5-SEAP, pGL3-basic, pUC57, pcDNA3.1-EGFP, ect.
产品说明书
pDRIVE-β-Kin(human) Map 产品说明书(点击下载)
pDRIVE-β-Kin(human) Sequence 产品说明书(点击下载)
产品说明
Description:
Kinesins are tubulin molecular motors whose function is to transport organelles within cells. Kinesins have been characterized as tetrameric proteins, with two heavy (α) chains and two light (β) chains. The promoter region of the β-kinesin gene can drive the constitutive expression of a transgene in a variety of cells. The 5’UTR is able to form a stable double hairpin structure that increases the strength of the promoter by enhancing mRNA translatability. The β-kinesin promoter encompassing the 5’UTR is 75-fold to 100-fold higher than the HSV-tk or NSE promoters [1].
1. Chernajovsky Y. et al. 1996. Human kinesin light (β) chain gene: DNA sequence and functional characterization of its promoter and first exon. DNA Cell Biol 15(11):965-974.
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