PR10067_启动子库_赢润生物
您好,欢迎光临赢润生物技术商城
请登录    |     免费注册     帮助中心

客服热线:18507311342

QQ咨询:7128088

订货邮箱:service@yrgene.com

当前位置: 首页 > 启动子库

启动子产品信息

订购信息

货号 种属 载体 描述 价格 周期
PR10067 Human pGL3-basic 询价 5-7 周

产品参数

Gene Promoter: FerH : Ferritin Heavy Chain
Specificity: Ubiquitous
Backbone: pDRIVE, pDRIVE5-SEAP, pGL3-basic, pUC57, pcDNA3.1-EGFP, ect.

产品说明书

pDRIVE-FerH/RU5'(human) Map 产品说明书(点击下载)

pDRIVE-FerH/RU5'(human) Sequence 产品说明书(点击下载)

产品说明

Description:
Ferritin H prom / HTLV 5’UTR

Ferritin is a ubiquitous iron storage protein, whose major role is to sequester and detoxify intracellular iron that has not been utilized in cellular metabolism. Ferritin is a 24 subunit protein composed of two subunit types, termed H (heavy) and L (light), which perform complementary functions in the protein. The H subunit plays a role in the rapid detoxification of iron whereas the L subunit facilitates long-term iron storage. The synthesis of ferritin is highly regulated by the iron status of the cell. The iron regulation is achieved at the translational level through interaction between a 28-nucleotide iron-responsive element (IRE), located in the 5’ untranslated region (5’UTR) of ferritin mRNAs, and a cytosolic protein, the iron regulatory protein [1]. To eliminate the iron regulation of the ferritin promoters, the 5’UTR of FerH and FerL have been replaced by the 5’UTR of the HTLV or EF-1α.


1. Eisenstein RS & Munro HN. 1990. Translational regulation of ferritin synthesis by iron. Enzyme 44(1-4):42-58.
2. Bevilacqua MA et al. 1992. Promoter for the human ferritin heavy chain-encoding gene (FERH): structural and functional characterization. Gene 15;111(2):255-60.

立即购买 加入购物车

长沙赢润生物技术有限公司版权所有 湘ICP备15013987号-2